• What is Colistin
  • Colistimethate Uses
  • Colistin Side effect
  • Colistin Indications
Colistimethate for Injection, USP is a sterile parentera antibiotic product which, when reconstituted (see Reconstitution), is suitable for intramuscular or intravenous administration. Each vial contains colistimethate sodium or pentasodium colistinmethanesulfonate (150 mg colistin base activity).
Colistimethate is an antibiotic used to treat certain bacterial infections. It works by stopping the growth of bacteria.
Colistin has also been used recently to treat ventilator-associated pneumonia (VAP) and bacteremia caused by MDR bacteria, such as P. aeruginosa, K. pneumoniae and A. baumannii. Alhough the use of colistin is considered to be effective, other antibiotics are often used in combination with colistin.
Acute Respiratory Distress Syndrome.
Breathing Changes.
Clostridium Difficile Infection.
Kidney Damage.
Life Threatening Allergic Reaction.
Nerve Function Blockage That Affects Normal Muscle Action.
Periods Of Not Breathing.
Seizures.
Colistimethate sodium aerosol (Promixin; Colomycin Injection) is used to treat pulmonary infections, especially in cystic fibrosis. In the UK, the recommended adult dose is 1–2 million units (80–160 mg) nebulised colistimethate twice daily.
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